| Entry |
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| Definition |
Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
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| Equation |
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| Comment |
steroid 16alpha-hydroxylase
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| Reaction class |
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| Enzyme |
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| Pathway |
| rn00140 | Steroid hormone biosynthesis |
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| Brite |
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.1
R03408 Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
1.14.14.-
R03408 Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
IUBMB reaction hierarchy [BR:br08202]
1. Oxidoreductase reactions
1.14.14.1
R04122 Alkane <=> ROH
R03408 Dehydroepiandrosterone <=> 16alpha-Hydroxydehydroepiandrosterone
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| Orthology |
| K07415 | cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-] |
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